I am posting the complete results as well as Dr. Dodds recommendations. Mabel is perfect. We don't have anything to worry about!
Dear Anna: Please see attached lab results for Mabel. You had additional
questions -- which I'll try to cover below:
Her demodex is due to a suppressed immune system from all the stress anfd
illness of her abandonment. [Bless you for saving her ! ] Liver
dysfunction is not present any more, so she's just very sensitive to drugs
given . Amitraz is particularly prone to producing adverese effects so IF
she tolerates the Amiraz collar, that fine, but I wouldn't dip her in it
again. You could try Goodwinol ointment on any smaaler spots of demodex.
They also use selamectin (Revolution) and ivermectin (Heartgard) for
mange -- but I think these could react with her as well -- can both br
liver toxic. Advocate could be uin the same category.
As she's had Ehrlichia, the Ehrlichia canis serum antibody level can be high
for months otr longer, and this does not mean that she's still infected. If
she stays well, then you don't need to retreat with doxycycline.
Her diet seems perfect. Best wishes. JeanLab Results:
ANTECH DIAGNOSTICS 17672-A Cowan Avenue Irvine CA 92614 Phone: 800-745-4725
Hemopet/Hemolife Client # 20073
11330 Markon Dr Chart # N
Garden Grove, CA 92841 on Raw Diet
Tel: 714-891-2022 8 ½ hrs post-pill Thyrosyn 0.6 mg SID
Fax: 714-891-2123
Accession No. Doctor Owner Pet Name Received
HPBC00193481 WALKER MULDOON MABEL 01/23/2007
Anna
Species Breed Sex Pet Age Reported
Canine Bloodhound SF 3Yrs (2-4 Yrs) 01/24/2007 07:45 AM
80 lbs
Test Requested Results Reference Range Units
T3 (RIA)
T3 (RIA) 74 45-150 ng/dL
FREE T4 (RIA)
Free T4 (RIA) 1.07 0.45-2.06 ng/dL
T4
T4 3.61 1.0-4.0 mg/dL
T3 AUTOANTIBODIES
T3 Autoantibodies 1.3 Less Than 2.0
T4 AUTOANTIBODIES
T4 Autoantibodies 1.3 Less Than 2.0
FREE T3
Free T3 2.8 1.7-5.3 pg/mL
COMPLETE BLOOD COUNT
WBC 14.1 4.0-15.5 103/mL
RBC 6.1 4.8-9.3 106/mL
HGB 14.8 12.1-20.3 g/dL
HCT 44 36-60 %
MCV 71 58-79 fL
MCH 24.1 19-28 pg
MCHC 34 30-38 %
Comment
RBC MORPHOLOGY NORMAL
Differential Absolute %
Neutrophils 9306 66 2060-10600 /mL
Lymphocytes 3243 23 690-4500 /mL
Monocytes 564 4 0-840 /mL
Eosinophils 846 6 0-1200 /mL
Basophils 141 1 0-150 /mL
Platelet Estimate Adequate
Platelet Count 341 170-400 103/mL
SUPERCHEM
AST (SGOT) 28 15-66 IU/L
ALT (SGPT) 113 12-118 IU/L
Total Bilirubin 0.1 0.1-0.3 mg/dL
Alkaline Phosphatase 173 (HIGH) 5-131 IU/L
GGT 7 1-12 IU/L
Total Protein 7.0 5.0-7.4 g/dL
Albumin 3.9 2.7-4.4 g/dL
Globulin 3.1 1.6-3.6 g/dL
A/G Ratio 1.3 0.8-2.0
Cholesterol 151 92-324 mg/dL
BUN 25 6-25 mg/dL
Creatinine 0.7 0.5-1.6 mg/dL
BUN/Creatinine Ratio 36 (HIGH) OK 4-27
Phosphorus 5.4 2.5-6.0 mg/dL
Calcium 10.9 8.9-11.4 mg/dL
Glucose 93 70-138 mg/dL
Amylase 815 290-1125 IU/L
Lipase 170 77-695 IU/L
Sodium 139 139-154 mEq/L
Potassium 3.9 3.6-5.5 mEq/L
Na/K Ratio 35 27-38
Chloride 102 102-120 mEq/L
CPK 93 59-895 IU/L
Triglyceride 50 29-291 mg/dL
Magnesium 1.8 1.5-2.5 mEq/L.
1/25/2007
Dear Colleague and Anna: Thyroid and other levels are good on the current dose of supplement, but are unlikely to be sustained over 24 hours (half life of thyroxine is 12-16 hours). As the T3 and freeT3 are normal, a non-thyroidal influence on these results is ruled out.
However, given her demodex and generally poor condition since rescue, a better steady state for control of hypothyroidism would be to spit the daily dose of thyroxine morning and night. Suggest switching her to 0. 4 – 0. 5 mg thyroxine twice daily – a modest total dose for her size.
The very high liver enzymes found at spay on Jan 10 have now essentially resolved. This means she likely had adverse effects from the medications used to control her demodex. Jean
Adult Optimal Levels T4 3-5 g/dl FT4 1-3 ng/dl T4AA < 2.0
T3 50-150 ng/dl FT3 3-8 pg/ml T3AA < 2.0
X Optimal therapeutic response levels should be in the upper 1/3 to 25% above the upper limits of the resting optimal ranges at 4-6 hours post-BID thyroid medication.
X Thyroid levels would be stabilized over 24 hrs by switching her to 0. 4 – 0. 5 mg thyroxine twice daily. Recommend retesting in ~ 6 months at 4-6 hrs post-dose.
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posguru@graceba.net